The National Bank of Organs and Tissues
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Uruguay is a country located in the southeast part of South America, with 176.215 square kilometers and 3.322.141 people (19/km2). The population is 48% male and 52% female and the life expectancy is 74.5 years. |
Uruguay plays an active role in the Mercosur, and the total gross domestic product is 21 billion dollars.
The transplantation activity is governed by transplant law 14.005, the National Bank of Organs and Tissues (BNOT), and has financial support from the financial law 16.343 and the Found of National Resources (FNR).
The transplant law of 1971 was the first in Latin America. Based on informed consent, it allows people to register positive or negative willingness to be a donor upon death.
Donors might be:
1. Alive: any adult from 18 up, that by his own willingness, expresses his consent to donate, once his death occurs.
2. Deceased: without former expression of a negative willingness
· With a Heart Strike
· With Brain Death
Consent might be given by:
Spouse, legitimate or natural children, parents, siblings, adopted children, ascendants or descendants ( 2nd. Degree ) and collateral relatives (3rd. Degree or higher)
The government Institution was created and regulated in 1977 and opened its doors in 1978. This service operates through the State University Medical School and the Public Health Secretary, sharing academic, normative and administrative responsibilities.
BNOT is responsible for:1) the National Register of Donors through signed informed consent; 2) the Procurement of donors; 3) the National Histocompatibility and Inmunogenetic Laboratory; and 4) the Tissue Bank.-
The Organization process:
1 - Procurement Donor Organization:
A) Unique Registry of Donors (RND).
Functions:
1. Maintain and register the documentation of informed consent.
B) Procurement Unit:
Functions:
1. Convert potential donors in real donors.
2. Recover viable organs and tissues.
3. Coordinate the interaction among Clinical team in surgery room.
4. Promote the organs and tissues donation.
OPOs (Organ Procurement Organizations)
2 - Unique Registry of Receptors Organizations:
A) Registry of organs and tissues request.
B) Unique and National Inmunogenetic and Histocompatibility Laboratory:
Functions:
1. Typify the organs and tissues receptors.
2. Typify living or death (in Hearth Strike or Brain Death) donors.
3. Allocate and deliver organs to the patients according to previous rules.
UNOS (United network for Organ Sharing)
3 - Multi tissues Bank:
Functions:
1. Selection of Hearth Strike donors.
2. Tissue extraction.
3. Discard or admit tissues to the processing succession
4. Conservation fresh tissues al – 4º Centigrade.
5. Conservation glycerolated tissues at - 80º Centigrade in dry ice.
6. Crioconservation cells and tissues (cardiac valves, vessels, etc) in Liquid Nitrogen at – 196º - 120º Centigrade.
7. Tissues registry.
8. Allocate tissues to the receptors according to previous rules.
9. Project RLA/7/009 ARCAL LIX of International Atomic Energy Agency “Quality System for the production of irradiated sterilized grafts”.
4 - Administrative and Accountant Office:
Functions:
1. Administer the economics resources.
2. Operate according to the T.O.C.A.F. (Accounting and financial administration text).
Strategies and tools in public and professional awareness for organ and tissue bank in Uruguay.
SINDOME
BONE MARROW DONORS WORLDWIDE
In Celebration of 10,000,000 United Donors Worldwide
HISTORY OF BONE MARROW TRANSPLANTATION
Links:
NEW TECHNOLOGY IN OUR TISSUE BANK
The International Atomic Energy Agency trough the Project URU/7/005 “Sterilizing Human Tissue Using Ionizing Radiation”, has order the purchase of an Irradiator Gammacell 220 Excel for the National Bank of Organs and Tissues.(BNOT) on July 14th of 2005.-
This equipment will be installed soon in the physical area of the BNOT, in order to irradiate human tissues produced in our Tissue Bank.
The advantage of sterilizingwith ionizing radiations is that it does not leave toxic residues in the grafts, and it allows to maintainthe tissue preservation temperature and so it is biological properties during the irradiation process.-
As it is known, in Uruguay for more than 25 years the National Organization - BNOT has been providing to the uruguayan population reliable grafts for implant and transplant.
Nowadays, our country does not count with an appropriate source to radiosterilize grafts. The existence of adequate technology in our country, will allow an important increase in the production of radiosterilized grafts with clinic and microbiological increased reliability.
The project will benefit the clinical users and all the patients from the public and private heath care system in the country.-
Link: www.iaea.org